Le Covid-19 “est beaucoup plus grave que la grippe”, et a tué trois fois plus

24/12/20 | 0 | 0 | 691 εμφανίσεις

Au printemps 2020, la mortalité dans les hôpitaux français liés au Covid-19 était le triple de celle de la grippe saisonnière de 2018-2019. Pourtant, il s’agissait de la pire saison de grippe depuis cinq ans.

Au printemps 2020 en France, le Covid-19 a plus tué trois fois plus que la grippe saisonnière de l’année passée, rapporte une étude de l’Inserm publiée dans le Lancet Respiratory Medicine. Les adolescents, bien que peu touchés dans l’ensemble, ont également été plus nombreux à décéder du Covid-19 que de la grippe, le principal facteur de risque étant le surpoids et l’obésité. Ces résultats soulignent l’importance de l’accès à un traitement et un vaccin contre le Covid-19.
Les épidémies de grippe et de Covid-19 sont deux maladies respiratoires ayant des modes de transmission similaires. “Cette étude est la plus importante à ce jour permettant de comparer les deux maladies et confirme que la Covid-19 est beaucoup plus grave que la grippe”, commente dans un communiqué la Pr Catherine Quantin du CHU de Dijon, et chercheuse à l’Inserm. Pour arriver à cette conclusion, les chercheurs ont compilé les données des hôpitaux français du printemps 2020 – du 1er mars au 30 avril – et les ont comparées avec celles de la grippe saisonnière du 1er décembre 2018 au 28 février 2019.
Liera aussi http://www.defenddemocracy.press/le-covid-19-est-beaucoup-plus-grave-que-la-grippe-et-a-tue-trois-fois-plus/

Comparison of the characteristics, morbidity, and mortality of COVID-19 and seasonal influenza: a nationwide, population-based retrospective cohort study

December 17, 2020
Background
To date, influenza epidemics have been considered suitable for use as a model for the COVID-19 epidemic, given that they are respiratory diseases with similar modes of transmission. However, data directly comparing the two diseases are scarce.
Methods
We did a nationwide retrospective cohort study using the French national administrative database (PMSI), which includes discharge summaries for all hospital admissions in France. All patients hospitalised for COVID-19 from March 1 to April 30, 2020, and all patients hospitalised for influenza between Dec 1, 2018, and Feb 28, 2019, were included. The diagnosis of COVID-19 (International Classification of Diseases [10th edition] codes U07.10, U07.11, U07.12, U07.14, or U07.15) or influenza (J09, J10, or J11) comprised primary, related, or associated diagnosis. Comparisons of risk factors, clinical characteristics, and outcomes between patients hospitalised for COVID-19 and influenza were done, with data also stratified by age group.
Findings
89 530 patients with COVID-19 and 45 819 patients with influenza were hospitalised in France during the respective study periods. The median age of patients was 68 years (IQR 52–82) for COVID-19 and 71 years (34–84) for influenza. Patients with COVID-19 were more frequently obese or overweight, and more frequently had diabetes, hypertension, and dyslipidaemia than patients with influenza, whereas those with influenza more frequently had heart failure, chronic respiratory disease, cirrhosis, and deficiency anaemia. Patients admitted to hospital with COVID-19 more frequently developed acute respiratory failure, pulmonary embolism, septic shock, or haemorrhagic stroke than patients with influenza, but less frequently developed myocardial infarction or atrial fibrillation. In-hospital mortality was higher in patients with COVID-19 than in patients with influenza (15 104 [16·9%] of 89 530 vs 2640 [5·8%] of 45 819), with a relative risk of death of 2·9 (95% CI 2·8–3·0) and an age-standardised mortality ratio of 2·82. Of the patients hospitalised, the proportion of paediatric patients (<18 years) was smaller for COVID-19 than for influenza (1227 [1·4%] vs 8942 [19·5%]), but a larger proportion of patients younger than 5 years needed intensive care support for COVID-19 than for influenza (14 [2·3%] of 613 vs 65 [0·9%] of 6973). In adolescents (11–17 years), the in-hospital mortality was ten-times higher for COVID-19 than for influenza (five [1·1% of 458 vs one [0·1%] of 804), and patients with COVID-19 were more frequently obese or overweight
Read more at https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(20)30527-0/fulltext#seccestitle140

Category: International

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